Human pluripotent founder cells (hPFCs) play a role in the generation of human iPS cells by initiating and establishing pluripotency in culture.
The hPFC discovery reported in Cell was lead by Dr. Mick Bhatia at McMaster UniversityMcMaster University. The group worked with colleagues at Harvard University and Australia to create a repository of data about these founder cells accessible to scientists worldwide. Thousands of individual founder cells were analyzed to create a database of their similarities and differences.