Person attributes
O'Keeffe first came to public attention in 2008, playing a member of the Royal Family who enjoys parties, one night stands and drugs in the music video for Falling Down, the last single released by Oasis before the band dissolved. That same year, she had a part in the feature film Abraham's Point.
In 2010 and 2012, O'Keeffe played Sadie in both seasons of BBC Three's drama series Lip Service, about a group of lesbians living in Glasgow, Scotland. In 2012 and 2013 she played Abbey Smith in the lead ensemble for the final two seasons of E4's comedy-drama Misfits, about a group of young offenders in a London community service program who obtain supernatural powers. In 2013, O'Keeffe had roles in television episodes of Law & Order: UK and Peaky Blinders, and appeared in the feature films Filth and Svengali. In 2015, she starred as Fedora, the side-kick and lover of the main antagonist in ITV's TV series, Jekyll and Hyde.