Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
September 25, 2018
Patent Application Number
14388224
Date Filed
March 27, 2013
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The invention relates to an artificial nucleic acid molecule comprising at least one 5′UTR element which is derived from a TOP gene, at least one open reading frame and optionally at least one 3′UTR element comprising a nucleic acid sequence which is preferably derived from the 3′UTR of a gene providing a stable mRNA, such as an albumin gene, or from a variant of the 3′UTR of a gene providing a stable mRNA. The invention further relates to the use of such an artificial nucleic acid molecule in gene therapy and/or genetic vaccination.
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