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US Patent 10273211 Metabolites of N-{4-([6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Patent 10273211 was granted and assigned to Exelixis Ltd on April, 2019 by the United States Patent and Trademark Office.

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Patent Applicant

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

April 30, 2019

Patent Application Number

14776337

Date Filed

March 17, 2014

Patent Citations

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Patent Citations Received

US Patent 12064430 Kinase inhibitor salts and compositions thereof

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US Patent 11065240 Drug combinations to treat multiple myeloma

US Patent 11760726 Crystalline solid forms of N-{4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl} -n'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use

US Patent 11969419 Method of treating cancer

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US Patent 10501418 Crystalline solid forms of N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use

US Patent 11564915 Cabozantinib dosage form and use in the treatment of cancer

US Patent 10851061 Crystalline solid forms of N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use

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Patent abstract

The invention relates to metabolites of cabozantinib (I) as well as uses thereof.

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