Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Rebecca Jayne Munro0
Alastair David Griffiths Lawson0
Daniel John Lightwood0
James Philip O'Connell0
John Robert Porter0
Date of Patent
November 16, 2021
0Patent Application Number
164709990
Date Filed
December 13, 2017
0Patent Citations Received
Patent Primary Examiner
Patent abstract
It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.
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