Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Timothy M. Miller
Sarah Devos
Frank Rigo
C. Frank Bennett
Date of Patent
October 10, 2023
Patent Application Number
16298607
Date Filed
March 11, 2019
Patent Citations
...
Patent Citations Received
Patent Primary Examiner
Patent abstract
Disclosed herein are methods for reducing expression of Tau mRNA and protein in an animal with Tau antisense compounds. Also disclosed are methods for modulating splicing of Tau mRNA in an animal with Tau antisense compounds. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Examples of neurodegenerative diseases that can be treated, prevented, and ameliorated with the administration Tau antisense oligonucleotides include Alzheimer's Disease, Fronto-temporal Dementia (FTD), FTDP-17, Progressive Supranuclear Palsy, Chronic Traumatic Encephalopathy, Epilepsy, and Dravet's Syndrome.
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