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US Patent 11919908 Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors

Patent 11919908 was granted and assigned to Incyte on March, 2024 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Liangxing Wu0

Cheng-Tsung Lai0

Onur Atasoylu0

Andrew W. Buesking0

Wenqing Yao0

Padmaja Polam0

Date of Patent

March 5, 2024

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Patent Application Number

175557680

Date Filed

December 20, 2021

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Patent Citations

US Patent 8524867 Optimized antibodies that target CD19

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US Patent 8637235 Identification of a JAK2 mutation in polycythemia vera

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US Patent 8785639 Substituted dihydropyrazolo[3,4-D]pyrrolo[2,3-B]pyridines and methods of use thereof

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US Patent 8852931 Identification of a JAK2 mutation involved in vaquez polyglobulia

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US Patent 9115133 Substituted fused tricyclic compounds, compositions and medicinal applications thereof

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US Patent 9233985 Arginase inhibitors as therapeutics

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US Patent 9321730 Method of making and administering quinoline derivatives as anti-cancer agents

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US Patent 9493419 Quinoline derivatives as anti-cancer agents

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Patent Citations Received

US Patent 12084430 Tricyclic urea compounds as JAK2 V617F inhibitors

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Patent Primary Examiner

Douglas M Willis

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CPC Code

0

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Patent abstract

The present application provides deazaguaine compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.

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