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US Patent 7498317 Antibacterial agents and process for producing the same

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Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
74983170
Patent Inventor Names
Shusuke Hashimoto0
Hideyuki Shibata0
Itsuko Takagi0
Masato Nagaoka0
Date of Patent
March 3, 2009
0
Patent Application Number
110494230
Date Filed
February 2, 2005
0
Patent Primary Examiner
‌
Leigh C. Maier
0
Patent abstract

An antibacterial agent showing a high affinity for Helicobactor pyroli and having an antibacterial effect specific to H. Pyroli. The agent has a chemical structure wherein an antibacterial substance is bonded to a sulfated polysaccharide or an oligosaccharide prepared by partial decomposition of the sulfated polysaccharide. Preferable embodiments are those having the chemical structure represented by Y—OCH(AH2NHR)n or Y—BH2NHR, wherein Y represents a sulfated polysaccharide or an oligosaccharide prepared by partial decomposition of the sulfated polysaccharide; A a carbon derived from aldehyde group occurring through the reduction of the reduced end sugar of Y and subsequent oxidation of the resulting product with an oxidant; B a carbon derived from the aldehyde group at the reduced end sugar of Y; R an antibacterial substance with a primary amino group or with an amino group introduced therein or represents an antibacterial substance derivative prepared by bonding an antibacterial substance through a spacer to the carbon A or the carbon B; and n=1 or 2.

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