Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
David Halford Ashton Jones0
Abraham Bout0
Date of Patent
May 26, 2009
Patent Application Number
12070145
Date Filed
February 14, 2008
Patent Primary Examiner
Patent abstract
The present invention provides immortalized eukaryotic cells and methods useful for the production of immunologically active bivalent antibody fragments, such as F(ab′)2 fragments. The methods and cells of the invention result in a desirable ratio of bivalent to monovalent antibody fragments.
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