Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jeffry Dean Watkins0
Alain Philippe Vasserot0
Craig Duane Dickinson0
Jirong Lu0
Date of Patent
May 11, 2010
Patent Application Number
12428558
Date Filed
April 23, 2009
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention encompasses isolated antibodies, or antigen-binding portions thereof, that specifically bind mature human IL-1 Beta. These antibodies, or antigen-binding portions thereof, generally exhibit high binding affinities (low kooff values), reduced deamidation compared to the native antibody, and can be used to treat various diseases such as rheumatoid arthritis, osteoarthritis, or neuroinflammation.
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