Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Juqun Shen0
Zhenping Zhu0
Date of Patent
June 22, 2010
0Patent Application Number
121484820
Date Filed
April 17, 2008
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention is directed to novel PDGFRβ-specific antagonists. The antagonists include antibodies, which can be bispecific. The antibodies are used to reduce or inhibit tumor growth and or to treat an angiogenic disease. The invention also includes combinations of PDGFRβ-specific antagonists with VEGFR antagonists for such treatments. The antagonists can further be administered in combination with other anti-angiogenic or anti-neoplastic drugs.
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