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US Patent 9828373 2-amino-pyrido[2,3-D]pyrimidin-7(8H)-one derivatives as CDK inhibitors and uses thereof

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Changchung Cheng0

Bing Liu0

Linlin Nie0

Mingyu Guan0

Shun Bai0

Xuke Li0

Yingjun Zhang0

Date of Patent

November 28, 2017

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Patent Application Number

153183660

Date Filed

July 23, 2015

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Patent Citations Received

US Patent 11746102 Polymorphs of selinexor

US Patent 11753401 Polymorphs of Selinexor

US Patent 11945794 Nuclear transport modulators and uses thereof

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US Patent 12084453 Bicyclic amines as CDK12 inhibitors

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US Patent 11945785 Pyrazine compounds as inhibitors of FLT3

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US Patent 11787771 Hydrazide containing nuclear transport modulators and uses thereof

Patent Primary Examiner

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Patent abstract

The invention provides compounds as CDK small-molecule inhibitors and uses thereof, the compounds can be used for treating inflammation and cell proliferation diseases. The novel compound of the invention is a powerful cyclin-dependent kinase 4 (CDK 4) or cyclin-dependent kinase-6 (CDK 6) inhibitor.

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