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Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces {the components being pressed through sieves, screens or meshes which obstruct the whole diameter of the tube the sieves, screens or meshes being cylinders or cones which obstruct the whole diameter of the tube, the flow changing from axial in radial and again in axial}