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Cytokine Hemoadsorption in ECMO Patients

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Contents

clinicaltrials.gov/study/NCT04901338
Is a
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Clinical study
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Clinical Study attributes

NCT Number
NCT049013380
Health Conditions in Trial
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Septic shock
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Cytokine storm
0
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Cardiogenic shock
0
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Cardiac arrest
0
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SIRS
0
Trial Recruitment Size
250
Clinical Trial Start Date
June 1, 2017
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Primary Completion Date
January 31, 2021
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Study Completion Date
January 31, 2021
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Clinical Trial Study Type
Observational0
Observational Clinical Trial Type
Case-Only0
Observational Study Perspective
Retrospective0
Official Name
Cytokine Hemoadsorption in ECMO Patients0
Last Updated
May 25, 2021
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Study summary

Cytokine hemoadsorption is a novel therapy used to improve outcome in critically ill patients with a dysregulated cytokine response and hemodynamic instability. Patients on extracorporeal membraneous oxygenation (ECMO) often develop severe systemic inflammatory response syndrome (SIRS). Cytokine removal using different types of hemoadsorption devices is believed to block the vicious circle of inflammation dysregulation when other basic therapeutic measures fail. To date there are very limited reports on ECMO and cytokine hemoadsorption combination therapy. The aim of this retrospective study is to evaluate feasibility and effectiveness of hemoadsorption in veno-arterial and veno-venous ECMO patients.

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