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Effects of Vitamin D on Skeletal Muscle Strength in Resistance Trained Adult Females

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clinicaltrials.gov/study/NCT05489666
Is a
‌
Clinical study
0

Clinical Study attributes

NCT Number
NCT054896660
Trial Recruitment Size
400
Trial Sponsor
Auburn University
Auburn University
0
Clinical Trial Start Date
September 1, 2022
0
Primary Completion Date
November 30, 2022
0
Study Completion Date
February 1, 2023
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Basic Science0
Intervention Type
Dietary Supplement0
Intervention Name
Nature Made Vitamin D3 5,000 IU, 125mcg0
Placebo0
Interventional Trial Phase
Not Applicable0
Official Name
Effects of Vitamin D on Skeletal Muscle Strength in Resistance Trained Adult Females0
Last Updated
August 10, 2022
0
Allocation Type
Randomized0
Intervention Model
Parallel Assignment0
Masking Type
Double0
Masked Party
Investigator0
Participant0
Study summary

The majority of vitamin D research has been done in non-athletic populations, particularly older populations, to analyze muscle weakness, pain, balance, and fractures. It has been reported that over a billion people worldwide are vitamin D deficient, including 36-70% of the young adult population. Previous literature also suggests that, even among healthy athletes, over 50% of subjects sampled had inadequate or insufficient vitamin D levels. Vitamin D deficiency can occur in young women, including pregnant women, and the risk of deficiency is even higher with advancing age in a woman's lifecycle. It is known that preserving skeletal muscle (SM) function is critical for women of all ages to prevent sarcopenia. Two factors in preserving SM are protein intake and resistance training. Relatively unknown are the actions of Vitamin D on SM function. Vitamin D deficiency can have a negative effect on SM function . However, additional research is needed to investigate the increase in SM strength when the serum concentration of vitamin D is improved. It is possible that an athlete may require an increased intake of vitamin D to assure adequate availability and storage for optimal performance; however, is known that food sources of vitamin D are limited in sufficient quantity to meet these requirements. Athletes who are insufficient will require a supplement of vitamin D3 for up to 5000 IU/day for at least eight weeks, to potentially reach optimal levels, then 1000-2000 IU/day for maintenance.

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