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Subsequently, he did his doctoral research at Vallabhbhai Patel Chest Institute which earned him a PhD from the University of Delhi. His post-doctoral training was at the Lerner Research Institute of Cleveland Clinic and on his return to India, he joined the Defence Institute of Physiology and Allied Sciences (DIPAS) as a scientist at grade D at its Genomics division which he headed. He moved to his alma mater, Jamia Millia Islamia that year where he holds the position of a professor at the department of biotechnology. He worked among the Indian armysoldiers stationed in Siachen Glacier to study the effect of high altitude on venous thrombosis and his studies were published in the Proceedings of the National Academy of Sciences of the United States of America. He has published a number of articles; ResearchGate, an online repository of scientific articles has listed 34 of them. Ashraf resides in Delhi, along the Mall Road.