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Stress, Adjustment And Growth In Children With Cancer And Their Parents

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clinicaltrials.gov/study/NCT01044160
Is a
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Clinical study
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Clinical Study attributes

NCT Number
NCT010441600
Health Conditions in Trial
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Posttraumatic growth
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Posttraumatic stress disorder
Posttraumatic stress disorder
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Trial Recruitment Size
6630
Trial Sponsor
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital
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Trial Collaborator
0
Clinical Trial Start Date
July 7, 2009
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Primary Completion Date
July 7, 2026
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Study Completion Date
July 7, 2026
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Clinical Trial Study Type
Observational0
Observational Clinical Trial Type
Case-Control0
Observational Study Perspective
Prospective0
Participating Facility
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital
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Official Name
Stress, Adjustment And Growth In Children With Cancer And Their Parents0
Last Updated
August 7, 2023
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Study summary

This proposal examines trauma and growth responses in the childhood cancer experience. It addresses a number of gaps and unanswered questions in the literature, while integrating several distinct but related lines of research. The rationale for this proposal is outlined briefly as follows: 1. Traumatic stress models focused on pathology dominate pediatric psychosocial oncology research despite empiric evidence of low levels of post-traumatic stress in this population. 2. The assumption of 'cancer as a traumatic event' has biased research designs (including lack of control comparisons) to focus on deficits and pathological outcomes. 3. This deficit-oriented approach has stimulated the development of interventions to treat or prevent PTSD, which may be unnecessary or even harmful. 4. Theoretical and empiric evidence suggests that a more common response to traumatic stress is growth and positive change, but posttraumatic growth phenomenon have been understudied in pediatric populations. 5. Cognitive and personality factors are important determinants of PTSD and positive growth outcomes, and some constructs from positive psychology theory may be particularly relevant in children with cancer. 6. Empirically, parents of children with cancer appear to be at higher risk of PTSD/PTSS, although results are not unequivocal, and the same research biases have applied to parental outcomes. This proposal includes assessment of parental PTSS and PTG, both as an outcome and a predictor of child outcomes.

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