Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Aimee Cossins0
Philip Marks0
Matthew Beard0
Date of Patent
July 24, 2018
0Patent Application Number
144272340
Date Filed
October 31, 2013
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides a nucleic acid sequence comprising a sequence of contiguous nucleotides, wherein said sequence of contiguous nucleotides has at least 90% sequence identity to the nucleic acid sequence of SEQ ID NO: 1, and wherein said sequence of contiguous nucleotides encodes a single-chain BoNT/E1 protein. The present invention also provides methods for producing soluble single-chain BoNT/E1 protein in an E. coli host cell, together with methods for producing soluble di-chain BoNT/E1 protein.
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