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US Patent 10035768 C5aR antagonists

Patent 10035768 was granted and assigned to ChemoCentryx on July, 2018 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Pingchen Fan0

Ju Yang0

Kevin Lloyd Greenman0

Manmohan Reddy Leleti0

Yandong Li0

Yibin Zeng0

Hiroko Tanaka0

Jay Powers0

Date of Patent

July 31, 2018

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Patent Application Number

157228190

Date Filed

October 2, 2017

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Patent Citations Received

US Patent 11951214 Capsule formulations

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US Patent 11479553 5-5 fused rings as C5a inhibitors

US Patent 11485737 Diaryl substituted 5,5-fused ring compounds as C5aR inhibitors

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US Patent 10759807 Diaryl substituted 5,5-fused ring compounds as C5aR inhibitors

US Patent 10828285 Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors

US Patent 11026935 Free base crystalline form of a complement component C5a receptor

US Patent 11603356 Amorphous form of a complement component C5a receptor

US Patent 11608336 Prodrugs of fused-bicyclic C5aR antagonists

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Patent Primary Examiner

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Patent abstract

Compounds are provided that are modulators of the C5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of C5a receptors.

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