US Patent 10036019 Bicyclic carbocyclic nucleosides and oligomeric compounds prepared therefrom
Patent 10036019 was granted and assigned to Ionis Pharmaceuticals on July, 2018 by the United States Patent and Trademark Office.
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Patent abstract
The present invention provides novel bicyclic carbocyclic nucleosides and oligomeric compounds prepared therefrom. Incorporation of one or more of the bicyclic carbocyclic nucleosides into an oligomeric compound is expected to enhance one or more properties of the oligomeric compound. In certain embodiments, the oligomeric compounds provided herein hybridize to a portion of a target RNA resulting in modulation of normal function of the target RNA. In certain embodiments, bicyclic carbocyclic nucleosides are provided as monomers for use as antivirals.
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Patent Inventor Names
Eric E. Swayze0
Punit P. Seth0
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US Patent 10036019 Bicyclic carbocyclic nucleosides and oligomeric compounds prepared therefrom
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Patent jurisdiction
Patent number
10036019
Date of patent
July 31, 2018
Patent application number
15125634
Date Filed
March 17, 2015
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