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US Patent 10040823 In vivo methods of monitoring biodistribution

Patent 10040823 was granted and assigned to Kode Biotech on August, 2018 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Kode Biotech
Kode Biotech
Current Assignee
Kode Biotech
Kode Biotech
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10040823
Date of Patent
August 7, 2018
Patent Application Number
15490471
Date Filed
April 18, 2017
Patent Primary Examiner
‌
Johann R. Richter
Patent abstract

Functional-lipid constructs of the structure F-S-L are disclosed, wherein F comprises a tyrosine or histidine residue, S is a spacer covalently linking F to L and L is a lipid. The functional residue may be iodinated and used to radiolabel a biological entity with 1251 and the iodinated constructs are used in a non-invasive method of monitoring the distribution of a biological entity in vivo.

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