Patent 10060921 was granted and assigned to Alnylam Pharmaceuticals on August, 2018 by the United States Patent and Trademark Office.
Disclosed herein are methods for reducing or arresting an increase in a Neuropathy Impairment Score (NIS) or a modified NIS (mNIS+7) in a human subject by administering an effective amount of a transthyretin (TTR)-inhibiting composition.