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US Patent 10065949 Method of preparing glucosylceramide synthase inhibitors

Patent 10065949 was granted and assigned to Genzyme on September, 2018 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Rayomand Gimi0

Jin Zhao0

Michael Reardon0

Craig S. Siegel0

Date of Patent

September 4, 2018

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Patent Application Number

155934400

Date Filed

May 12, 2017

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Patent Citations Received

US Patent 12083115 Methods for treating neurological symptoms associated with lysosomal storage diseases

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US Patent 10604518 Method of preparing glucosylceramide synthase inhibitors

US Patent 10954230 Method of preparing glucosylceramide synthase inhibitors

US Patent 11857512 Pharmaceutical compositions comprising venglustat

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US Patent 12060349 Glucosylceramide synthase inhibitors

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Patent Primary Examiner

Niloofar Rahmani

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Patent abstract

The invention relates to a method of preparing inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

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