Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
September 25, 2018
Patent Application Number
14117286
Date Filed
May 16, 2012
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to the construction of a new class of Targeted Secretion Inhibitors (TSIs), which comprise a non-cytotoxic protease, translocation peptide and a targeting moiety peptide, wherein the targeting moiety peptide has a free N-terminal domain and a free C-terminal domain; to a single-chain fusion protein precursor thereof, and to a method of activating said single-chain fusion protein precursor.
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