Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Daniel R. McMasters0
Pengcheng P. Shao0
Stephane L. Bogen0
Wanying Sun0
Alexander J. Kim0
Christian Fischer0
Chunhui Huang0
Dann L. Parker, Jr.0
...
Date of Patent
October 2, 2018
Patent Application Number
15532548
Date Filed
December 1, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to tricyclic compounds of formula (I) which are inhibitors of one or more mutant IDH enzymes: (I); wherein A is —C(R1)= or —N═; and X is selected from the group consisting of: (II-i), (II-ii), (I) (II-iii), and (II-iv). The present invention is also directed to uses of the tricyclic compounds described herein in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.
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