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US Patent 10100115 Methods for the treatment of vascularizing cancers

Patent 10100115 was granted and assigned to MacroGenics on October, 2018 by the United States Patent and Trademark Office.

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Patent abstract

The invention concerns therapeutic compositions for the treatment of vascularizing cancers, especially, glioblastoma. In particular, the invention is directed to compositions that comprise a molecule having a binding ability that is specific for B7-H3 and a molecule having a binding ability that is specific for a cell-surface factor (or its receptor) that is involved in promoting tumor angiogenesis (especially VEGF or its receptor, VEGFR). The invention is additionally directed to the use of such compositions in the treatment of such cancers, and in particular, in the treatment of glioblastoma.

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Patent Inventor Names
Andrew S. Chi0
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Infobox
Is a
Patent
Patent
0
Patent Applicant
MacroGenics
MacroGenics
0
Current Assignee
MacroGenics
MacroGenics
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
101001150
Date of Patent
October 16, 2018
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Patent Application Number
151180100
Date Filed
February 11, 2015
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Patent Citations Received
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US Patent 10683364 Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof
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US Patent 11254747 Covalent diabodies and uses thereof
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Patent Primary Examiner
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Lynn A Bristol
0
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Patent citations received
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US Patent 11254747 Covalent diabodies and uses thereof
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 US Patent 10100115 Methods for the treatment of vascularizing cancers

Infobox
Is a
Patent
Patent
Patent applicant
MacroGenics
MacroGenics
Current assignee
MacroGenics
MacroGenics
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
10100115
Date of patent
October 16, 2018
Patent application number
15118010
Date Filed
February 11, 2015
Patent primary examiner
‌
Lynn A Bristol

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