US Patent 10101333 Methods for affinity maturation-based antibody optimization
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Patent abstract
Provided herein is a rational method of affinity maturation to evolve the activity of an antibody or portion thereof based on the structure/affinity or activity relationship of an antibody. The resulting affinity matured antibodies exhibit improved or optimized binding affinity for a target antigen.
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Patent Inventor Names
Helen Hongyuan Mao0
Vaughn Smider0
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US Patent 10101333 Methods for affinity maturation-based antibody optimization
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Is a
Patent applicant
Patent jurisdiction
Patent number
10101333
Date of patent
October 16, 2018
Patent application number
14692646
Date Filed
April 21, 2015
Patent primary examiner
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