Systems and methods for buoyancy compensation are provided. Both active and passive buoyancy compensation can be provided using a compressible mixture made of a liquid along with a hydrophopic material such as a powder, electrospun fiber, or foam. The compressible fluid compresses as pressure is applied or expands as pressure is released thereby substantially maintaining an overall neutral buoyancy for a vessel. This allows the vessel to ascend and descend to water depths with minimal active buoyancy change. As a result, the energy usage and the reliance on higher pressure air and oils can be minimized.