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US Patent 10159666 Dosing of cabozantinib formulations

Patent 10159666 was granted and assigned to Exelixis Ltd on December, 2018 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

December 25, 2018

Patent Application Number

15126767

Date Filed

March 17, 2015

Patent Citations Received

US Patent 12064430 Kinase inhibitor salts and compositions thereof

0

US Patent 10851061 Crystalline solid forms of N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use

US Patent 11065240 Drug combinations to treat multiple myeloma

US Patent 11760726 Crystalline solid forms of N-{4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl} -n'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use

US Patent 10501418 Crystalline solid forms of N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use

US Patent 11564915 Cabozantinib dosage form and use in the treatment of cancer

Patent Primary Examiner

Taofiq A. Solola

Patent abstract

The invention relates to administration of various pharmaceutical formulations of N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, (cabozantinib) a c-Met inhibitor, and its metabolites, to achieve desirable pharmacokinetic and pharmacodynamic effects.

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