Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David Butler0
Meena0
Naoki Iwamoto0
Nenad Svrzikapa0
Gregory L. Verdine0
Ivan Zlatev0
Date of Patent
December 25, 2018
0Patent Application Number
151121460
Date Filed
January 16, 2015
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present invention relates to chirally controlled oligonucleotides of select designs, chirally controlled oligonucleotide compositions, and methods of making and using the same. In some embodiments, a provided chirally controlled oligonucleotide composition provides different cleavage patterns of a nucleic acid polymer than a reference oligonucleotide composition. In some embodiments, a provided chirally controlled oligonucleotide composition provides single site cleavage within a complementary sequence of a nucleic acid polymer.
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