Ventilated aero-structures include a micro-lattice structure operatively coupled to a honeycomb core. The interface between the honeycomb core and the micro-lattice structure is configured to permit air flow to and from the honeycomb core via the micro-lattice structure. Aircraft include a ventilated aero-structure and a ventilation system configured to circulate air through the ventilated aero-structure. Some methods include coupling a micro-lattice structure to a honeycomb core. Some methods include utilizing a ventilated aero-structure to assemble an aircraft.