A programmable battery protection system. Implementations may include a battery protection integrated circuit (IC) with an array of fuses, a plurality of latches coupled with the array of fuses, a plurality of MOSFETs coupled with the plurality of latches, and a plurality of resistors coupled in series and in parallel with each one of the plurality of MOSFETs. The IC may also include a comparator coupled with the plurality of resistors and with a battery control circuit. Whether any one of the array of fuses is open or closed (remains closed) may be set by a fuse trimming signal from the battery control circuit. A voltage supplied to the comparator by the plurality of resistors during operation may be one of a discharge overcurrent threshold voltage, a charge overcurrent threshold voltage, or a short current threshold voltage.