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US Patent 10206924 Small molecule inhibitors of EGFR and PI3K

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Judith S. Leopold0

Christopher Emil Whitehead0

Date of Patent

February 19, 2019

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Patent Application Number

155365280

Date Filed

December 15, 2015

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Patent Citations Received

US Patent 11357857 Excipient compounds for protein processing

US Patent 11660343 Viscosity-reducing excipient compounds for protein formulations

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US Patent 11672865 Viscosity-reducing excipient compounds for protein formulations

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US Patent 11673876 Substituted aminobenzyl heteroaryl compounds as EGFR and/or PI3K inhibitors

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US Patent 11696951 Viscosity-reducing compounds for protein formulations

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Patent Primary Examiner

Shirley V Gembeh

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Patent abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.

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