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US Patent 10207990 Salts and prodrugs of 1-methyl-D-tryptophan

Patent 10207990 was granted and assigned to NewLink Genetics on February, 2019 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent Applicant
NewLink Genetics
NewLink Genetics
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Current Assignee
NewLink Genetics
NewLink Genetics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
102079900
Patent Inventor Names
Sanjeev Kumar0
Hong Zhuang0
Jesse Waldo0
Mario Mautino0
Firoz Jaipuri0
Hima Potturi0
Date of Patent
February 19, 2019
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Patent Application Number
156346100
Date Filed
June 27, 2017
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Patent Citations Received
‌
US Patent 11485705 Salts and prodrugs of 1-methyl-d-tryptophan
Patent Primary Examiner
‌
Raymond J. Henley, III
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Patent abstract

Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.

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