Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Lei Fang0
Bingshi Guo0
Jingwu Zang0
Zhengyi Wang0
Date of Patent
February 19, 2019
Patent Application Number
16100019
Date Filed
August 9, 2018
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided are anti-PD-L1 antibodies or fragments thereof. The antibodies or fragments thereof specifically bind to the immunoglobulin C domain of the PD-L1 protein. In various example, the antibodies or fragments thereof include a VH CDR1 of SEQ ID NO: 1, a VH CDR2 of SEQ ID NO: 2, a VH CDR3 of SEQ ID NO: 3, a VL CDR1 of SEQ ID NO: 4, a VL CDR2 of SEQ ID NO: 5, and a VL CDR3 of SEQ ID NO: 6, or variants of each thereof. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and infectious diseases are also provided.
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