Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have one of the following structures (I), (II) or (III):

Edits on 2 Oct, 2023

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Golden AI

edited on 2 Oct, 2023

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Infobox

Patent Inventor Names

Jun Feng0

Liansheng Li0

Pingda Ren0

Tao Wu0

Yi Liu0

Yuan Liu0

Yun Oliver Long0

Edits on 3 May, 2023

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Golden AI

edited on 3 May, 2023

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Infobox (+1 properties)

Infobox

Patent Citations Received

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US Patent 11639346 Quinazoline derivatives as modulators of mutant KRAS, HRAS or NRAS

Edits on 27 Apr, 2023

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Golden AI

edited on 27 Apr, 2023

Infobox

Patent Citations Received

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US Patent 11021470 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof

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Golden AI

edited on 26 Apr, 2023

Infobox

Patent Citations Received

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US Patent 10875842 Inhibitors of KRAS G12C mutant proteins

Edits on 25 Apr, 2023

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Golden AI

edited on 25 Apr, 2023

Infobox

Patent Citations Received

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US Patent 10919850 Covalent inhibitors of KRas G12C

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Golden AI

edited on 25 Apr, 2023

Infobox

Patent Citations Received

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US Patent 11236068 Fused ring compounds

Edits on 23 Apr, 2023

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Golden AI

edited on 23 Apr, 2023

Infobox

Patent Citations Received

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US Patent 10975071 Inhibitors of KRAS G12C mutant proteins

Edits on 7 Apr, 2023

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Golden AI

edited on 7 Apr, 2023

Infobox

Patent Citations Received

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US Patent 10723738 Inhibitors of KRAS G12C mutant proteins

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Golden AI

edited on 6 Apr, 2023

Infobox

Patent Citations Received

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US Patent 11279689 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1 yl)prop-2-en-1-one derivatives and similar compounds as KRAS G12C modulators for treating cancer

Edits on 4 Apr, 2023

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Golden AI

edited on 4 Apr, 2023

Infobox

Patent Citations Received

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US Patent 11059819 Fused hetero-hetero bicyclic compounds and methods of use thereof

Edits on 2 Apr, 2023

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Golden AI

edited on 2 Apr, 2023

Infobox

Patent Citations Received

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US Patent 10858343 Inhibitors of KRAS G12C mutant proteins

Edits on 31 Mar, 2023

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Golden AI

edited on 31 Mar, 2023

Infobox

Patent Citations Received

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US Patent 10829458 Substituted quinazoline compounds and methods of use thereof

Edits on 30 Mar, 2023

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Golden AI

edited on 30 Mar, 2023

Infobox

Patent Citations Received

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US Patent 11358959 Benzothiophene and benzothiazole compounds and methods of use thereof

Edits on 25 Mar, 2023

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Golden AI

edited on 25 Mar, 2023

Infobox

Patent Citations Received

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US Patent 11377441 Covalent inhibitors of KRAS

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Golden AI

edited on 24 Mar, 2023

Infobox

Patent Citations Received

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US Patent 11274093 Fused bicyclic benzoheteroaromatic compounds and methods of use thereof

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