Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Claudio Mapelli0
Paul E. Morin0
R. Michael Lawrence0
Xiaojun Han0
Cort S. Madsen0
Dasa Lipovsek0
Gene M. Dubowchik0
Michael C. Myers0
...
Date of Patent
April 23, 2019
Patent Application Number
15891492
Date Filed
February 8, 2018
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.
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