An anti-theft packaging case having double bottoms and double covers includes a top cover portion, side plates, and a bottom plate portion. The top cover portion includes an upper cover, a lower cover, a left cover, and a right cover. The bottom plate portion includes a left bottom plate, a right bottom plate, an inner bottom plate, and an outer bottom plate. The upper cover is provided with a tear strip and an anti-theft line. The tear strip is provided with a strengthening rib. The anti-theft packaging case having double bottoms and double covers greatly reduces risks that the sealing of the packaging case is broken and the packaging case is cracked or stolen, and has very good anti-theft performance.