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US Patent 10280171 Heterocyclic inhibitors of PTPN11

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Barbara Czako0

Jason Cross0

Paul Leonard0

Philip Jones0

Connor Austin Parker0

Faika Mseeh0

Date of Patent

May 7, 2019

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Patent Application Number

156071740

Date Filed

May 26, 2017

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Patent Citations Received

US Patent 12084447 SHP2 phosphatase inhibitors and methods of use thereof

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US Patent 11466017 Heterocyclic inhibitors of PTPN11

US Patent 11034705 Fused tricyclic ring derivatives as Src homology-2 phosphate inhibitors

US Patent 11591336 Substituted pyrazolo[3,4-b]pyrazines as SHP2 phosphatase inhibitors

US Patent 11629145 SHP2 phosphatase inhibitors and methods of use thereof

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US Patent 11701354 Pyrazolo[3,4-b]pyrazine derivatives as SHP2 phosphatase inhibitors

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US Patent 11840536 Heterocyclic inhibitors of PTPN11

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US Patent 11890281 SHP2 phosphatase inhibitors and methods of making and using the same

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Patent Primary Examiner

Samantha L Shterengarts

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Patent abstract

The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.

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