US Patent 10295719 Cylindrical light diffusing device for use in photoimmunotherapy

The present invention provides a cylindrical light diffusing device comprising a non-circular core fiber having (i) a fiber core that provides a “top hat” core irradiance distribution; (ii) light blocking means that prevent frontal light emisson from distal end of the non-circular core fiber; and (iii) a light diffusing section having a diffusing proximal end, a diffusing distal end, and internal scattering features distributed within the fiber core of the light diffusing section along central axis of the fiber core, wherein the light diffusion section emits irradiance in a radially symmetric longitudinally “top hat” diffusing irradiance distribution.