Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 28, 2019
Patent Application Number
13474120
Date Filed
May 17, 2012
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides ungulates, including pigs, expressing CTLA4-Ig, as well as tissue, organs, cells and cell lines derived from such animals. Such animals, tissues, organs and cells can be used in research and medical therapy, including xenotransplanation. In addition, methods are provided to prepare organs, tissues and cells expressing the CTLA4-Ig for use in xenotransplantation, and nucleic acid constructs and vectors useful therein.
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