Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yongliang Yang0
Date of Patent
June 11, 2019
Patent Application Number
15550783
Date Filed
February 3, 2016
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides an isothiocyanate compound and its application. The compound is an aryl-substituted isothiocyanate compound that has a structure of the general formula I. The isothiocyanate compound of the present invention has very good solubility in water, far better inhibitory activity for XPO1 protein than other non-aryl substituted congeneric compounds, little side effects, and good biological safety and bioavailability, and is quite suitable for clinical application. Therefore, the isothiocyanate compound would have tremendous potential market space and economic benefits.
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