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US Patent 10316029 Dual mechanism inhibitors for the treatment of disease

Patent 10316029 was granted and assigned to Aerie Pharmaceuticals on June, 2019 by the United States Patent and Trademark Office.

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Patent

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Current Assignee
Aerie Pharmaceuticals
Aerie Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10316029
Date of Patent
June 11, 2019
Patent Application Number
15941783
Date Filed
March 30, 2018
Patent Citations Received
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US Patent 11590123 Ophthalmic compositions
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US Patent 11707460 Ophthalmic compositions
0
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US Patent 11618748 Dual mechanism inhibitors for the treatment of disease
0
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US Patent 12018012 Aryl cyclopropyl-amino-isoquinolinyl amide compounds
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US Patent 11891376 Aryl cyclopropyl-amino-isoquinolinyl amide compounds
0
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US Patent 10654844 Dual mechanism inhibitors for the treatment of disease
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US Patent 11028081 Dual mechanism inhibitors for the treatment of disease
Patent Primary Examiner
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D Margaret M Seaman
Patent abstract

Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.

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