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US Patent 10323003 Process for the preparation of a PDE4 inhibitor

Patent 10323003 was granted and assigned to Chiesi Farmaceutici S.p.A. on June, 2019 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Chiesi Farmaceutici S.p.A.
Chiesi Farmaceutici S.p.A.
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Current Assignee
Chiesi Farmaceutici S.p.A.
Chiesi Farmaceutici S.p.A.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
103230030
Patent Inventor Names
Alessandro Falchi0
Fausto Pivetti0
Orsola Vecchi0
Rocco Bussolati0
Caterina Ventrici0
Edoardo Mariani0
Emanuele Ferrari0
Emilio Lutero0
...
Date of Patent
June 18, 2019
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Patent Application Number
158027370
Date Filed
November 3, 2017
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Patent Citations Received
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US Patent 11352327 Process for the preparation of a PDE4 inhibitor
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US Patent 11981639 Process for the preparation of a PDE4 inhibitor
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US Patent 10759761 Process for the preparation of a PDE4 inhibitor
Patent Primary Examiner
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Daniel R Carcanague
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Patent abstract

The present invention relates to a process for the preparation of compounds endowed with phosphodiesterase (PDE4) inhibitory activity having formula (I). The invention also relates to the process for the isolation by crystallization of the compound (I) and to its use for the preparation of pharmaceutical compositions for inhalation in combination with suitable carriers or vehicles. The present invention also relates to solvates and crystal forms of a compound of formula (I). The synthesized product is suitable for use in pharmaceutical applications for instance in the treatment of respiratory diseases.

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