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US Patent 10335432 Microporous zirconium silicate for the treatment of hyperkalemia

Patent 10335432 was granted and assigned to zs pharma on July, 2019 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
zs pharma
zs pharma
Current Assignee
zs pharma
zs pharma
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10335432
Date of Patent
July 2, 2019
Patent Application Number
15254688
Date Filed
September 1, 2016
Patent Primary Examiner
‌
Kortney L. Klinkel
Patent abstract

The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of particles into the bloodstream of the patient. Also disclosed is a method for preparing high purity crystals of UZSi-9 exhibiting an enhanced level of potassium exchange capacity. These compositions are particularly useful in the therapeutic treatment of hyperkalemia.

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