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US Patent 10352945 Optogenetic probes for measuring membrane potential

Patent 10352945 was granted and assigned to President and Fellows of Harvard College on July, 2019 by the United States Patent and Trademark Office.

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Patent abstract

The invention provides methods, cells and constructs for optical measurement of membrane potential. These methods can be used in cells that are not accessible to presently available methods using electrodes. The methods can be directed to, for example, high-throughput drug screening assays to determine agents that can affect membrane potential of a target cell.

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