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US Patent 10385320 Recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Nicole K. Paulk0

Mark A. Kay0

Date of Patent

August 20, 2019

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Patent Application Number

153677340

Date Filed

December 2, 2016

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Patent Citations Received

US Patent 11459558 Methods for using transcription-dependent directed evolution of AAV capsids

US Patent 12084653 Methods for using transcription-dependent directed evolution of AAV capsids

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US Patent 12084654 Methods for using transcription-dependent directed evolution of AAV capsids

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US Patent 12091435 Antibody-evading virus vectors

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US Patent 12104163 Adeno-associated virus vectors for treatment of Rett syndrome

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US Patent 12116384 Virus vectors for targeting ophthalmic tissues

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US Patent 10745447 Methods and compositions for antibody-evading virus vectors

US Patent 11840555 Methods and compositions for antibody-evading virus vectors

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...

Patent Primary Examiner

M Franco G Salvoza

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Patent abstract

The present invention relates to variant AAV capsid polypeptides, wherein the variant AAV capsid polypeptides exhibit increased transduction and/or tropism in human muscle tissue or cells as compared non-variant parent capsid polypeptides.

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