Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Caroline H. Ko0
Chad A. Mirkin0
David A. Giljohann0
Janina Luciano0
Samuel A. Jensen0
Alexander Stegh0
Date of Patent
September 3, 2019
Patent Application Number
15858142
Date Filed
December 29, 2017
Patent Citations Received
Patent Primary Examiner
Patent abstract
Polyvalent nanoconjugates address the critical challenges in therapeutic use. The single-entity, targeted therapeutic is able to cross the blood-brain barrier (BBB) and is thus effective in the treatment of central nervous system (CNS) disorders. Further, despite the tremendously high cellular uptake of nanoconjugates, they exhibit no toxicity in the cell types tested thus far. This property is critical for therapeutic agent delivery applications for reducing off-target effects.
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