Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Arnold Oliphant0
Morassa Mohseni Middleton0
Pinar Iyidogan0
Ying Lin Liu0
Brittany A. Rohrman0
Fabian Block0
Mark C. Wallen0
Michael James Schmidt0
Date of Patent
September 3, 2019
0Patent Application Number
163553610
Date Filed
March 15, 2019
0Patent Citations
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
Methods, compositions, kits and apparatuses that include a fluid, the fluid containing a ternary complex and Li+, wherein the ternary complex includes a primed template nucleic acid, a polymerase, and a nucleotide cognate for the next correct base for the primed template nucleic acid molecule. As an alternative or addition to Li+, the fluid can contain betaine or a metal ion that inhibits polymerase catalysis such as Ca2+. In addition to Li+, the fluid can contain polyethylenimine (PEI) with or without betaine.
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