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US Patent 10406165 Compounds targeting proteins, compositions, methods, and uses thereof

Patent 10406165 was granted and assigned to BioTheryX on September, 2019 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides modulators of protein function, to restore protein homeostasis, including GSPT1 activity. The invention provides methods of modulating protein-mediated diseases, such as GSPT1-mediated diseases, disorders, conditions, or responses. Compositions are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as GSPT1-mediated diseases, disorders, and conditions, including cancer and astrogliosis.

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